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Your Parkinson's News Update for the Week of 10.12.20

Monday October 12, 2020
Discovery of Key Feature of Alpha-Synuclein
May Lead to New Treatment
Molecular Neurodegeneration via Parkinson's News Today
"The team at Purdue University and their colleagues set out to better understand how alpha-synuclein aggregates form by comparing human and mouse versions of the protein. While both humans and mice produce alpha-synuclein, the exact structure and sequence of the protein varies among different organisms — with some important biochemical consequences."
Scientists Uncover New Clues about Parkinson’s
Science Advances via Massachussetts Institute of Technology
"Beta-band oscillations are normally observed in parts of the brain that control movement when a person is paying attention or planning to move. It’s not clear what they do or why they are disrupted in patients with Parkinson’s.
But because patients’ symptoms tend to be worst when beta activity is high — and because beta activity can be measured in real time with sensors placed on the scalp or with a deep-brain stimulation device that has been implanted for treatment, researchers have been hopeful that it might be useful for monitoring the disease’s progression and patients’ response to treatment. In fact, clinical trials are already underway to explore the effectiveness of modulating deep-brain stimulation treatment based on beta activity."
Rebuilding Your Life With Hope
Parkinson's News Today
Sherri Woodbridge's column, "Journeying Through Parkinson's Disease", regularly features her experiences and insight on life impacted by Parkinson's. Her latest piece stands out as a beacon of HOPE: Sherri and her family's mobile home was one of only 33 (in a total of 225) that remained inhabitable after wildfires tore through Southern Oregon:
"As I walk around this now-unfamiliar place and smell the unfamiliar air that surrounds the unfamiliar sights, I still shed tears for the known and the unknown. As I walk among the charred and bent shapes of what used to be other people’s homes, it makes me think of my disease.
...If you look closely enough, you can see new life emerging from the ground near where you sit. It seems almost impossible, but it is there among the charred remains...enough to fill you with renewed hope."