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Filtered by: February 2009

Calculating gene and protein connections in a Parkinson's disease model

Thursday February 26, 2009

FINDINGS: Researchers have created an algorithm that meshes existing data to produce a clearer step-by-step flow chart of how cells respond to stimuli. Using this new method, Whitehead Institute and Massachusetts Institute of Technology scientists have analyzed alpha-synuclein toxicity to identify genes and pathways that can affect cell survival. Misfolded copies of the alpha-synuclein protein in brain cells are a hallmark of Parkinson's disease.

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Archimedes Pharma Announces Successful Proof-of-Concept Results on Two Intranasal Development Projects

Thursday February 26, 2009

Archimedes Pharma Limited, the pan-European specialty pharmaceutical company, today announces positive headline data from its recently completed proof-of-concept trials for two of its intranasal (IN) development projects. Both the IN Apomorphine and IN Diazepam Phase I studies showed high bioavailability, positive pharmacokinetics and good tolerability and confirmed that each candidate has the potential to replace existing formulations in high value markets. The agents are being developed for the treatment of motor fluctuations or "off episodes" in Parkinson's disease and Acute Repetitive Seizures ("ARS") in refractory epilepsy patients respectively.

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Familial tremor can vary in difficulty it presents

Thursday February 26, 2009

DEAR DR. DONOHUE: Some time ago, you wrote about a tremor that runs in families. I have a tremor and talked to my doctor, who referred me to a specialist because he thought I might have Parkinson's disease. My brother and I have a similar hand tremor. My sister has a shaking of her head.

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Brain-Machine Interfaces Make for Tricky Ethics

Thursday February 26, 2009

Direct connections from brains to computers may someday help free paralyzed people from the constraints of their bodies. They're already used to reverse deafness and blindness. But as they become more refined, brain-machine interfaces will almost certainly be used for non-therapeutic purposes — and with that expansion comes profound ethical questions.

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Man, machine and in between

Thursday February 26, 2009

Brain-implantable devices have a promising future. Key safety issues must be resolved, but the ethics of this new technology present few totally new challenges, says Jens Clausen.

Jens Clausen is at the Institute of Ethics and History in Medicine, University of Tübingen, Tübingen, Germany.

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Pesticide Use Linked to Increased Risk in Parkinson's Disease

Thursday February 26, 2009

Pesticide exposure may increase the risk of Parkinson's disease in some people. Individuals at increased risk appear to be those with certain genes that may make them particularly susceptible. These findings, published by scientists in California and Florida in the journal Environmental Health Perspectives, reported that individuals with high levels of pesticide exposure due to residence or occupation who have certain genes were at a 300 to more than a 400 percent increased risk for being diagnosed with Parkinson's disease.

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Led by Beate Ritz from UCLA, the researchers compared 324 patients with Parkinson's disease with 334 people without the disease who were living in rural California communities. They compared the groups with respect to the occurrence of specific gene

Thursday February 26, 2009

Scott Werny, who has worked tirelessly to help preserve Sunset Beach and Waimea Valley, protect beach access and prevent overdevelopment at Turtle Bay Resort, is now facing a personal battle.

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Frontline and New Book Highlight Effect of Parkinson's on Families

Thursday February 26, 2009

The recent Frontline special "My Father, My Brother, and Me" explored the effect that Parkinson's disease (PD) has on the children of PD patients, a topic also explored in a recently published book by Parkinson's in the Park founder Kay Mixson Jenkins.

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Homestead artist Ferraro deals with Parkinson's

Thursday February 26, 2009

For most of his life, Frank Ferraro, 47, had used his hands to create — first as a commercial printmaker, then as a full-time sculptor, working large slabs of stone.

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Spinning for The Davis Phinney Foundation

Thursday February 26, 2009

If you like to move indoors for cycling once the weather turns cold, then why not spin for a cause and support The Davis Phinney Foundation this Saturday?

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