NWPF

News ArchivesRead News

New Compound May Halt Parkinson's Disease Symptoms

Thursday February 13, 2014

The Times of India - WASHINGTON: Scientists have developed a novel compound that may protect against developing movement problems associated with Parkinson's disease (PD).

Parkinson's disease, which affects an estimated 4 million to 10 million people worldwide, is a progressive movement disorder with no known cure.

It is not known for certain what causes the disease, but research has shown that it's linked with the loss of nerve cells in the brain that secrete dopamine, a chemical that is involved in movement and emotion.

To find a potential new therapy for PD, researchers from South Korea searched for a way to shield these brain cells.

They made 56 compounds and tested them to see which ones boosted the production of proteins that protect dopamine-releasing neurons from damage.

Of those, one, which they call "12g," proved to be the most active. Interestingly, it protected mice from developing PD-like symptoms in one laboratory test.

"Taken together, 12g was found to effectively prevent the motor deficits that are associated with PD," researchers said.

The study appears in American Chemical Society's Journal of Medicinal Chemistry. 

(13 Feb 2014). The Times of India. New compound may halt Parkinson's disease symptoms. http://articles.timesofindia.indiatimes.com/2014-02-13/science/47304616_1_progressive-movement-disorder-movement-problems-parkinson

Recent News

May 20 - Book Review: Aging in the Key of Humor
May 19 - Press Release: The Michael J. Fox Foundation for Parkinson's Research Joins Multinational Critical Path for Parkinson's Consortium
May 19 - Congress reaches deal to overhaul chemical regulation
May 16 - Lifestyle: Why Parkinson's disease won't stop me rowing across the Pacific
May 16 - Many biomarkers for PD fail to inform on progression
May 10 - Parkinson's Cell Transplant Shows Good Reinnervation at 24 Years
May 7 - Growing art installation gathers stories of living with Parkinson's
May 5 - New technique can provide better cell transplants against Parkinson's disease
May 2 - What's Good For The Heart Is Good For The Brain
Apr 29 - Press Release: FDA approves first drug to treat hallucinations and delusions associated with Parkinson’s disease
Apr 28 - Dopamine-making neurons can be chemically controlled in animal model of Parkinson's
Apr 25 - Lifestyle: Dating with Disease
Apr 25 - Scientific breakthrough in fight against Parkinson's and Alzheimer's
Apr 20 - Breakthrough Parkinson's disease blood test
Apr 15 - Living with Parkinson's
Apr 12 - Tissue biomarker for dementia with Lewy bodies and Parkinson’s disease
Apr 11 - Yoga for Every Body: Experts say yoga can ease pain and improve mobility for people with neurologic conditions
Apr 9 - Commonly prescribed Parkinson's drugs up risk of compulsive gambling, shopping, binge eating, hypersexuality
Apr 7 - Pfizer and IBM Launch Innovative Research Project to Transform Parkinson's Disease Care
Apr 7 - Parkinson's Drug Highly Effective for Resistant Depression