News ArchivesRead News

Alzheimer's and Parkinson's: Is There a Genetic Overlap?

Monday August 05, 2013

Huffington Post - For years, scientists have wondered about a possible link between Alzheimer's and Parkinson's disease, either in terms of genetics or environmental factors.

But a new study shows that the two diseases do not appear to share a common genetic risk.

The study, by Dr. Valentina Moskvina of the Cardiff University School of Medicine in Wales, examined genetic data from 3,177 patients with Alzheimer's and 7,277 control patients, as well as 5,333 patients with Parkinson's and 12,298 control patients. The gene-based analyses found no significant evidence supporting the presence of loci -- or the specific locations of genes -- that were associated with increased risk for both Alzheimer's and Parkinson's.

"Our findings therefore imply that loci that increase the risk of both Parkinson's and Alzheimer's are not widespread and that the pathological overlap could instead be 'downstream' of the primary susceptibility genes that increase the risk of each disease," the study authors concluded in a press release.

More than 5 million Americans are living with Alzheimer's disease, while Parkinson's affects 1 in every 500 people.

Recent News

Nov 22 - A caregiver's story: Living and loving through the slow process of dying
Nov 19 - Testosterone cause of sex differences in the occurrence of Parkinson’s disease, new research suggests
Nov 18 - New strategy reduces side effects in Parkinson's treatment
Nov 14 - Opinion: The never-ending tests of Parkinson's disease
Nov 13 - Parkinson’s disease: A new tool for diagnosis
Nov 10 - Parkinson's Disease Drug May Be Useful For Delaying, Preventing Blindness In Older Population
Nov 9 - Microsoft VP’s diagnosis fuels employees’ heartfelt efforts to help others
Nov 6 - Lewy body dementia: unrecognized and misdiagnosed
Nov 5 - Gait difficulties in Parkinson's linked to new blood vessels in brain
Oct 30 - Special Section: Enabling Technologies for Parkinson’s Disease Management
Oct 27 - Scientists discover a 'switchboard' of molecules that protect against Parkinson's disease
Oct 26 - Dancing improves mobility and quality of life in people with Parkinson's
Oct 23 - The amazing woman who can smell Parkinson’s disease — before symptoms appear
Oct 20 - Personal Essay: The deviousness of dementia
Oct 19 - Mechanism that 'melts' protein clumps may lead to new Parkinson's treatments
Oct 19 - Researchers find that stem cell treatment may reduce cognitive impairment related to dementia with Lewy bodies
Oct 17 - Cancer Drug Helps Parkinson's Patients
Oct 12 - Researchers identify immune gene that can prevent Parkinson's disease and dementia
Oct 12 - Blog Post: An Alert, Well-Hydrated Artist in No Acute Distress
Oct 7 - This month, a brain surgery will be broadcast on live TV for the first time ever