News ArchivesRead News
Guideline issued for treating sleep, constipation, sexual problems in Parkinson's disease
Thursday March 18, 2010
St. Paul, MN - ST. PAUL, Minn. – The American Academy of Neurology has issued a new guideline recommending the most effective treatments to help people with Parkinson's disease who experience sleep, constipation, and sexual problems, which are common but often underrecognized symptoms. The guideline is published in the March 16, 2010, issue of Neurology, the medical journal of the American Academy of Neurology.
"While the main symptom of Parkinson's disease is movement problems, there are many other symptoms to be aware of, including sleep disorders, constipation, and problems with urination and sexual function," said lead guideline author Theresa A. Zesiewicz, MD, with the University of South Florida in Tampa and a Fellow of the American Academy of Neurology. "Without treatment, these symptoms can cause as much pain and discomfort as movement problems and greatly affect daily routines and quality of life."
Sexual problems often affect people with Parkinson's disease. In men with Parkinson's, erectile dysfunction is common. According to the guideline, the drug sildenafil citrate may improve erectile dysfunction. The guideline also found the drug isosmotic macrogol may improve constipation in people with Parkinson's disease.
For problems with excessive daytime sleepiness, the guideline recommends that doctors consider the drug modafinil to help people feel more awake. However, it's important to note that one study showed people taking modafinil had a false sense of alertness. This may pose a safety risk for activities such as driving. The guideline also found the drug methylphenidate may help with fatigue.
The guideline mentions two tests to help identify nonmotor symptoms of Parkinson's disease. One is the NMSQuest rating scale. The other is the Unified Parkinson's Disease Rating Scale (UPDRS). The original UPDRS mainly tests for movement problems. Doctors use the updated version of the UPDRS to test for all Parkinson's symptoms, including those unrelated to movements. People with Parkinson's disease should talk to their doctor about whether these tests may be helpful.
"More research is needed into these symptoms of Parkinson's disease since there are still a lot of unknown answers as to what causes these symptoms and how they can best be treated to improve lives," said Zesiewicz.
Recent NewsMay 15 - Study offers answers on life expectancy for people with Parkinson's disease, Lewy body dementia
May 5 - Parkinson's in a dish: Researchers reproduce brain oscillations
May 5 - ‘Hunger Hormone’ Could Help Treat Parkinson’s Disease
May 3 - Antibiotic doxycycline may offer hope for treatment of Parkinson's disease
May 1 - Impulse Control Disorders in Parkinson's Disease: Building Physician, Patient Awareness
Apr 28 - Does Parkinson’s disease begin in the gut?
Apr 28 - New empathy-creating digital device could be revolutionary for caregivers
Apr 24 - Treating Depression With Deep Brain Stimulation Works—Most of the Time
Apr 24 - Parkinson’s disease shows links to depression
Apr 21 - TOLEDO Trial: Apomorphine Infusions Reduce 'Off' Time in Parkinson's Disease
Apr 21 - New drug provides long-awaited breakthrough for Parkinson's psychosis
Apr 12 - Obstructive Sleep Apnea Affects Cognition in Parkinson's Disease
Apr 11 - Seattle boxing gym giving hope to Parkinson's patients
Apr 10 - A new rhythm
Apr 10 - Brain cells reprogrammed to make dopamine, with goal of Parkinson's therapy
Apr 6 - FDA allows marketing of first direct-to-consumer tests that provide genetic risk information for certain conditions
Apr 5 - Combatting the isolation of young onset Parkinson's disease
Apr 1 - The Kid is Alright
Mar 30 - Hepatitis Tied to Parkinson's Risk
Mar 28 - Elon Musk's new company said to see brain-computer link