NWPF

News ArchivesRead News

Reduced Diet May Offer Parkinson?s Help

Tuesday December 19, 2006

ISLAMABAD, December 15, 2006(Park Tribune) - A long-term low calorie diet, already reported to extend life span, may also offer protection from Parkinson’s disease- at least in monkeys.

Rhesus monkeys fed a diet that had 30 percent fewer calories than normal were less affected by a toxin that produces a Parkinson’s-like condition, researchers reported Monday.

Previous studies of similar reductions in food intake have shown that it extends the life span of mice.

The new study, by Mark P. Mattson of the National Institute on Aging, is reported in Proceedings of the National Academy of Science.

A team of researchers fed one group of monkeys the low calorie diet for six months, during which they lost about 12 percent of body weight compared to monkeys fed a normal diet.

Then both groups of primates were given a toxin which causes damage similar to Parkinson’s disease, causing the degeneration of dopamine neurons in the brain.

Movement was affected in all monkeys, but the ability to move and speed of movement were greater in the low-calorie monkeys than in those that had been fed normally.

The researchers found that the monkeys on a restricted diet had significantly higher concentrations than normal weight animals of two chemicals that protect nerve cells, BNDF and GNDF.

Intermittent fasting has been shown to increase levels of BNDF in rodents, the researchers noted. GNDF, they said, currently is being given to Parkinson’s patients in clinical trials.

"The present findings suggest the protective effect of reduced-calorie diets may result from the up-regulation of GNDF and BNDF expression," they wrote.

Recent News

Aug 22 - Parkinson's Disease Could Be Diagnosed Through Eye Check, Mice Help Researchers In Further Study
Aug 22 - Machine learning to unlock Parkinson's disease mystery
Aug 21 - Cognitive control plays major role in Parkinson’s Gait
Aug 15 - 'I've Never Felt Constrained': After Parkinson's Diagnosis, Chestnut Hill Man Turns To Drumming
Aug 11 - Virtual reality and treadmill training could help prevent falls in older adults
Aug 9 - New laboratory model replicates early phase of Parkinson's before onset of motor symptoms
Aug 8 - Marshall University Scientists Develop A New Approach For Parkinson’s Disease Therapy
Aug 5 - Cambuslang woman diagnosed with Parkinson's at 42 is set to trek through Alps
Aug 4 - Active Music Therapy May Be Beneficial in Parkinson's
Aug 1 - Mini-Brains? Scientists Grow Rice Grain-Sized Brains to Aid Parkinson’s Research
Jul 30 - Lab method sheds light on how genetic mutations cause inherited Parkinson's disease
Jul 27 - Indicators of Parkinson's disease risk found in unexpected places
Jul 24 - Parkinson's: Mutant gene interaction may pave the way for new treatments
Jul 22 - Boxing training used to fight against Parkinson's disease
Jul 17 - Stem cell treatment breakthrough could cure Parkinson’s patients
Jul 14 - Cancer drug shows early promise for Parkinson's disease
Jul 13 - Opinion: Dividing the Caregiving Responsibilities Between Siblings
Jul 12 - Researchers make advance in possible treatments for Gaucher, Parkinson’s diseases
Jul 11 - Parkinson’s Head Trauma Link Looks Even Stronger
Jul 7 - Penn students’ start-up XEED puts wearables to work against Parkinson’s disease