News ArchivesRead News
Cannabinoid Treatments May Offer Novel Therapy For Parkinson’s Disease
Thursday December 21, 2006
Frankfurt, Germany, December 21, 2006(Normal News) - Cannabis-based medicines could offer therapeutic relief for symptoms of Parkinson’s disease (PD) and may also moderate the course of the illness, according to a scientific review published this month in the journal Current Medicinal Chemistry.
"Cannabinoids are antioxidant, inhibit glutamate toxicity, and they also possess anti-inflammatory properties," authors state. "All together, we can conclude that cannabinoid-based medicines could be neuroprotective in the course of the disease, whereas [individual] compounds ... might modulate the behavioral effects of ... PD motor symptoms themselves."
Parkinson’s disease is a neurodegenerative disorder affecting the basal ganglia that results in a loss of motor coordination, organ failure, and death. The disease is characterized by a loss of dopaminergic neurons, typically resulting from brain inflammation, glutamate overproduction, and/or oxidative stress. The illness is estimated to affect approximately 2 percent of the population over age 65.
Survey data indicates that cannabis can provide subjective relief for symptoms of PD, including bradykinsia (extreme slowness of movement and reflexes), muscle rigidity, and tremor. However, a recent clinical trial assessing the short-term use of oral THC on symptoms of PD found the drug to have little immediate effect on patients’ movement.
For more information, please contact Paul Armentano, NORML Senior Policy Analyst, at (202) 483-5500. Full text of the study, "An overview of Parkinson’s disease and the cannabinoid system and possible benefits of cannabinoid-based treatments," appears in the December issue of Current Medicinal Chemistry
Recent NewsDec 8 - New technique scours the genome for genes that combat disease
Dec 8 - Restless sleep may be an early sign of Parkinson's, dementia
Dec 1 - Defects in cell's 'waste disposal system' linked to Parkinson's
Dec 1 - Dual virtual reality/treadmill exercises promote brain plasticity in Parkinson's patients
Nov 17 - 'Moving Day' participant is not letting young-onset Parkinson's disease stop him
Nov 17 - Focused ultrasound shows promise for treating Parkinson's tremor
Nov 17 - New research to target air pollution as a potential trigger for Parkinson’s
Nov 17 - This device will let you feel what it's like to suffer from Parkinson's
Nov 10 - How does Parkinson's disease influence depression?
Nov 10 - House votes to repeal ObamaCare's Medicare cost-cutting board
Nov 10 - Microsoft shows off watch that quiets Parkinson's tremors
Nov 3 - Utah group battling Parkinson's disease with boxing
Nov 3 - UVA-LED STUDY EXAMINES POTENTIAL OF SOUND WAVES TO MANAGE PARKINSON’S DISEASE
Oct 27 - Herbicide's link to Parkinson's disease
Oct 27 - NTU Singapore, KAIST scientists discover new mechanism that causes Parkinsonian symptoms
Oct 27 - 70,000 Washingtonians face higher insurance costs after Trump order, officials say
Oct 18 - Brain disconnections may contribute to Parkinson's hallucinations
Oct 18 - Fighting Parkinson's disease through dance
Oct 17 - Scientists Identify Structure of PINK1, Key Parkinson’s-protective Protein
Oct 17 - Diabetes drug cuts Parkinson's risk by 28 percent, study finds