News ArchivesRead News
Tumours found in rats given stem cells during Parkinson’s study
Thursday October 26, 2006
October 23, 2006 (CBC News) - A potential leap in the treatment of Parkinson’s disease has been tempered with a setback as rats injected with embryonic stem cells were essentially cured of Parkinson’s-like symptoms, but soon developed brain tumours.
When researchers at the University of Rochester transplanted human embryonic stem (HES) cells into the rats, "the implants yielded a significant, substantial and long-lasting restitution of motor function," according to a study published Monday in the online journal of Nature Medicine.
But after 10 weeks into the trial, the scientists discovered the tumours had begun to grow in every rat.
The findings are considered a blow to plans to use HES cells to grow tissues for human transplant.
Stem cells can be thought of as blank slates or cells that have yet to become specialized. They have the ability to become any type of cell to form skin, bones, organs or other body parts.
In particular, researchers have seen the potential for HES cell therapy in curing Parkinson’s because the disease requires only a single cell type that produces dopamine. Dopamine is a neurotransmitter that carries signals between neurons (brain cells).
The brain cells containing dopamine become injured or die in a Parkinson’s patient, which often leads to the person being unable to control physical movements, or they suffer from tremors.
Canada and several other countries have approved strict laws that limit research on stem cells from human embryos.
Recent NewsJul 7 - Parkinson’s Patients Have a Higher Risk of Developing Melanoma — and Vice Versa, Study Finds
Jun 27 - The rogue protein behind Parkinson’s disease may also protect your gut
Jun 26 - Do Statins Increase Risk of Parkinson’s Disease? Some Researchers Think So
Jun 22 - A Confused Immune System Could Be Behind Parkinson's Disease
Jun 21 - Predicting cognitive deficits in people with Parkinson’s disease
Jun 20 - Gym offers classes in noncontact boxing for Parkinson’s patients
Jun 19 - Human Limitations Could Prevent Us From Advancing in Science. AI Could Help.
Jun 13 - Brain Cell Transplants Are Being Tested Once Again For Parkinson's
Jun 12 - Smell Test May Sniff Out Oncoming Parkinson's and Alzheimer's
Jun 8 - Smartphones Track Motor Function in Parkinson's Disease
Jun 8 - GKC Enrolls First Patient in Personal KinetiGraph Trial as Part of NPF’s Parkinson’s Outcomes Project
Jun 8 - Low-fat dairy intake may raise Parkinson's risk
Jun 6 - Patient Voices: Parkinson's Disease
Jun 1 - World-First Trials Have Been Launched to Treat Parkinson's And Blindness With Embryonic Stem Cells
Jun 1 - LIFE Shared This Remarkable Parkinson's Disease Story in 1959.
May 24 - Survival Rates Differ Widely in Parkinson's, MSA, Lewy Bodies
May 22 - Discovery may offer hope to Parkinson's disease patients
May 15 - Study offers answers on life expectancy for people with Parkinson's disease, Lewy body dementia
May 5 - Parkinson's in a dish: Researchers reproduce brain oscillations
May 5 - ‘Hunger Hormone’ Could Help Treat Parkinson’s Disease