NWPF

News ArchivesRead News

Gene therapy Beneficial in Parkinson’s Disease

Thursday October 26, 2006

19 Oct 2006(MedIndia.com) - The initial studies of human gene therapy for Parkinson’s disease has given the green signal to technique showing it to safe, and useful in reducing symptoms for patients, according to the reports of two groups of researchers.

In the neuroscience meetings held yesterday and last week the researchers reported that each of the 24 patients who received therapy in the two separate trials received some benefit and none had significant side effects.

Katie Hood, deputy chief executive officer of the Michael J. Fox Foundation for Parkinson’s Research said that gene therapy had a tarnished reputation because of problems encountered in trials against other diseases.

In 1999 the Food and Drug Administration temporarily halted gene therapy trials after an 18-year-old who was treated for a mild genetic disorder died after a violent reaction to the procedure. in 2005 trials were again brought to a standstill after three French children who was treated for inherited immuno- deficiency disease developed leukemia and one of them died.

Hood said, ``It’s very encouraging that two companies were able to show benefits with no significant adverse effects. Safety is obviously the first hurdle."

Patients have been cautioned however against placing too much hope in the findings because Parkinson’s studies have been infamous for showing placebo effects. Researchers say that only when the techniques are tested in controlled trials, which are now in the planning stages, can they determine whether the benefits are real, and long-lasting or not.

Recent News

May 20 - Book Review: Aging in the Key of Humor
May 19 - Press Release: The Michael J. Fox Foundation for Parkinson's Research Joins Multinational Critical Path for Parkinson's Consortium
May 19 - Congress reaches deal to overhaul chemical regulation
May 16 - Lifestyle: Why Parkinson's disease won't stop me rowing across the Pacific
May 16 - Many biomarkers for PD fail to inform on progression
May 10 - Parkinson's Cell Transplant Shows Good Reinnervation at 24 Years
May 7 - Growing art installation gathers stories of living with Parkinson's
May 5 - New technique can provide better cell transplants against Parkinson's disease
May 2 - What's Good For The Heart Is Good For The Brain
Apr 29 - Press Release: FDA approves first drug to treat hallucinations and delusions associated with Parkinson’s disease
Apr 28 - Dopamine-making neurons can be chemically controlled in animal model of Parkinson's
Apr 25 - Lifestyle: Dating with Disease
Apr 25 - Scientific breakthrough in fight against Parkinson's and Alzheimer's
Apr 20 - Breakthrough Parkinson's disease blood test
Apr 15 - Living with Parkinson's
Apr 12 - Tissue biomarker for dementia with Lewy bodies and Parkinson’s disease
Apr 11 - Yoga for Every Body: Experts say yoga can ease pain and improve mobility for people with neurologic conditions
Apr 9 - Commonly prescribed Parkinson's drugs up risk of compulsive gambling, shopping, binge eating, hypersexuality
Apr 7 - Pfizer and IBM Launch Innovative Research Project to Transform Parkinson's Disease Care
Apr 7 - Parkinson's Drug Highly Effective for Resistant Depression