NWPF

News ArchivesRead News

Ibuprofen may curb risk of Parkinson’s disease

Thursday December 22, 2005

Dec 16, 2005(Reuters Health) - Regular use of the pain-relieving nonsteroidal anti-inflammatory drug (NSAID) ibuprofen (Motrin, Advil) may delay or prevent the onset of Parkinson’s disease, according to data from roughly 147,000 U.S. men and women enrolled in the Cancer Prevention Study II Nutritional Cohort.

In 1992, subjects provided information on four types of commonly used analgesics. In 2001, they provided information on the occurrence of Parkinson’s disease. The researchers detected 413 cases of Parkinson’s disease during follow up.

"We found that individuals who regularly used ibuprofen had about a 35 percent lower risk of developing Parkinson’s disease than non-users," Dr. Alberto Ascherio, of Harvard School of Public Health in Boston, Massachusetts, told Reuters Health.

Specifically, compared to those who did not use NSAIDs, users of 2 to 7 ibuprofen tablets per week had about a 28 percent reduced relative risk of developing Parkinson’s disease, while those who reported using 1 or more tablets per day had a 38 percent reduced risk of Parkinson’s.

No associations were observed between the risk of PD and the use of aspirin, other NSAIDs, or acetaminophen.

"These findings suggest that ibuprofen could contribute to the prevention of Parkinson’s disease," Ascherio said. "Because of the progressive nature of the degenerative process, it is also possible that this drug could be beneficial for individuals with Parkinson’s, but this should be tested in randomized clinical trials."

"It would be premature for people with Parkinson’s disease to start taking ibuprofen or other anti-inflammatory drugs," Ascherio cautioned. "Albeit promising, these findings are insufficient to support a change in current therapeutical practice."

Recent News

May 20 - Book Review: Aging in the Key of Humor
May 19 - Press Release: The Michael J. Fox Foundation for Parkinson's Research Joins Multinational Critical Path for Parkinson's Consortium
May 19 - Congress reaches deal to overhaul chemical regulation
May 16 - Lifestyle: Why Parkinson's disease won't stop me rowing across the Pacific
May 16 - Many biomarkers for PD fail to inform on progression
May 10 - Parkinson's Cell Transplant Shows Good Reinnervation at 24 Years
May 7 - Growing art installation gathers stories of living with Parkinson's
May 5 - New technique can provide better cell transplants against Parkinson's disease
May 2 - What's Good For The Heart Is Good For The Brain
Apr 29 - Press Release: FDA approves first drug to treat hallucinations and delusions associated with Parkinson’s disease
Apr 28 - Dopamine-making neurons can be chemically controlled in animal model of Parkinson's
Apr 25 - Lifestyle: Dating with Disease
Apr 25 - Scientific breakthrough in fight against Parkinson's and Alzheimer's
Apr 20 - Breakthrough Parkinson's disease blood test
Apr 15 - Living with Parkinson's
Apr 12 - Tissue biomarker for dementia with Lewy bodies and Parkinson’s disease
Apr 11 - Yoga for Every Body: Experts say yoga can ease pain and improve mobility for people with neurologic conditions
Apr 9 - Commonly prescribed Parkinson's drugs up risk of compulsive gambling, shopping, binge eating, hypersexuality
Apr 7 - Pfizer and IBM Launch Innovative Research Project to Transform Parkinson's Disease Care
Apr 7 - Parkinson's Drug Highly Effective for Resistant Depression